Methyl gamma-chloro-beta-hydroxybutyrate

Methyl gamma-chloro-beta-hydroxybutyrate - Names and Identifiers

Name	4-Chloro-3-hydroxy-butyricacidmethylester
Synonyms	Methyl chloro-3-hydroxybutyrate 4-Chloro-3-hydroxy-butyric acid Methyl 4-chloro-3-hydroxybutyrate Methyl 4-chloro-3-hydroxybutanoate methyl 4-chloro-3-hydroxybutanoate Methyl gamma-chloro-beta-hydroxybutyrate 4-Chloro-3-hydroxy-butyricacidmethylester 4-Chloro-3-hydroxybutanoic acid methyl ester 4-Chloro-3-hydroxy-butycir acid methyl ester Butanoic acid,4-chloro-3-hydroxy-, methyl ester
CAS	10488-68-3
InChI	InChI=1/C5H9ClO3/c1-9-5(8)2-4(7)3-6/h4,7H,2-3H2,1H3

Methyl gamma-chloro-beta-hydroxybutyrate - Physico-chemical Properties

Molecular Formula	C5H9ClO3
Molar Mass	152.58
Density	1.232
Boling Point	249℃
Flash Point	104℃
Vapor Presure	0.00387mmHg at 25°C
pKa	12.73±0.20(Predicted)
Refractive Index	1.458
Physical and Chemical Properties	Relative density of 1.255(19 degrees C), boiling point of 104 degrees C/12mmHg.

Methyl gamma-chloro-beta-hydroxybutyrate - Introduction

(R,S)-4-chloro-3-hydroxybutyric acid methyl ester, chemical formula C5H9ClO2. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: colorless liquid
-Boiling point: about 140-145 degrees Celsius
-Density: about 1.22g/cm³
-Solubility: Soluble in alcohol and ether solvents, insoluble in water

Use:
Methyl (R,S)-4-chloro-3-hydroxybutyrate is widely used in organic synthesis and can be used as an important intermediate. It is often used to synthesize drugs, pesticides and pharmaceutical chemicals. Specific uses include:
-Important intermediates in drug synthesis.
-an important intermediate in the synthesis of pesticides.
-Standards in chemical research and analysis.

Preparation Method:
Methyl (R,S)-4-chloro-3-hydroxybutyrate can be synthesized by the following steps:
1. Under the catalysis of sodium carbonate, the reaction of 4-chloro-3-hydroxybutyric acid and methanol.
2. The final product was purified by distillation. Methyl (R,S)-4-chloro-3-hydroxybutanoate.

Safety Information:
(R,S)-4-chloro-3-hydroxybutyric acid methyl ester is an organic compound, and safety precautions should be paid attention to when using and handling:
-Irritating to skin and eyes, rinse with water immediately after contact.
-in the use of the process to avoid inhalation of its steam or dust, as far as possible in a well-ventilated place to operate.
-Wear appropriate protective gloves, goggles and protective clothing when using.
-Storage should avoid contact with oxidants, acids or alkalis and other substances, avoid fire and high temperature.

Last Update：2024-04-09 19:05:44